Here are a few suggestions for your next trip from Mainz

In 4 hours, you can reach Paris, Bryssel, Luxemburg, Esch-sur-Alzette.

In 5 hours, you can reach Berlin, Amsterdam, Zürich, Hamburg, Rotterdam, Antwerpen.

In 6 hours, you can reach Schaan, Vaduz.

In 7 hours, you can reach London, Genève.

In 8 hours, you can reach Wien, Prag, Milano, Marseille.

In 9 hours, you can reach Bratislava, Birmingham, Brno.

In 10+ hours, you can reach Madrid, Rom, Bukarest, Budapest, Warszawa, Stockholm, Köpenhamn, Dublin, Zagreb, Ljubljana...