Sankt Gallen
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Here are a few suggestions for your next trip from Karlovy Vary

In 4 hours, you can reach Praha.

In 5 hours, you can reach München.

In 6 hours, you can reach Berlin, Linz.

In 7 hours, you can reach Wien, Brno, Ostrava.

In 8 hours, you can reach Bratislava, Hamburg.

In 9 hours, you can reach Brussel, Zürich, Schaan, Basel.

In 10+ hours, you can reach Roma, Paris, București, Budapest, Warszawa, Stockholm, København, Amsterdam, Zagreb, Ljubljana...